KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
38.48
Human Site:
Y216
Identified Species:
70.56
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
Y216
M
K
A
T
G
K
L
Y
A
C
K
K
L
N
K
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
Y212
V
R
A
T
G
K
M
Y
A
C
K
K
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
S26
R
G
S
F
D
G
S
S
S
Q
P
S
R
D
K
Dog
Lupus familis
XP_542675
460
51324
D158
Y
A
F
E
T
K
T
D
L
C
L
V
M
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
Y216
M
K
A
T
G
K
M
Y
A
C
K
K
L
N
K
Rat
Rattus norvegicus
Q63651
564
63750
Y216
M
K
A
T
G
K
M
Y
A
C
K
K
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
Y216
M
R
A
T
G
K
M
Y
A
C
K
K
L
N
K
Chicken
Gallus gallus
NP_990026
593
64642
Y246
R
R
A
T
G
K
M
Y
A
N
K
K
L
N
K
Frog
Xenopus laevis
NP_001087513
575
66421
Y212
V
R
A
T
G
K
M
Y
A
C
K
K
L
E
K
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
L131
K
F
Y
A
V
K
V
L
Q
K
K
A
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
Y335
V
R
A
T
G
K
M
Y
A
C
K
K
L
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
Y229
V
R
A
S
G
K
M
Y
A
L
K
K
L
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
Y438
K
K
D
T
Q
R
I
Y
A
M
K
V
L
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
73.3
6.6
13.3
N.A.
93.3
93.3
N.A.
86.6
73.3
73.3
20
N.A.
73.3
N.A.
60
N.A.
P-Site Similarity:
100
93.3
26.6
20
N.A.
100
100
N.A.
100
86.6
93.3
33.3
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
70
8
0
0
0
0
77
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
24
0
% E
% Phe:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
70
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% I
% Lys:
16
31
0
0
0
85
0
0
0
8
85
70
0
0
93
% K
% Leu:
0
0
0
0
0
0
8
8
8
8
8
0
77
8
0
% L
% Met:
31
0
0
0
0
0
62
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
39
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
0
% Q
% Arg:
16
47
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
8
0
0
8
8
8
0
0
8
0
8
0
% S
% Thr:
0
0
0
70
8
0
8
0
0
0
0
0
0
8
0
% T
% Val:
31
0
0
0
8
0
8
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _